Ginsenoside Rg1 defenses PC-12 cells against hydrogen peroxide-caused damage via up-regulation of miR-216a-5p
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چکیده
منابع مشابه
Quercetin protects PC-12 cells against hypoxia injury by down-regulation of miR-122
Objective(s): Impairment of nerve cells of brain induced by hypoxia results in energy-deprivation and dysfunction, which accompanies with neurons apoptosis. Improving function of nerve cells is important for treating cerebral anoxia. This study aimed to investigate the role of Quercetin (Quer) in hypoxia-induced injury of pheochromocytoma (PC-12) cells. Materials and Methods: PC-12 cells were c...
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BACKGROUND Although a number of medicines are available for the management of hypertension, the organ damage induced by hypertension is not resolved. The aim of this study was to investigate the protection of ginsenoside Rg1 (Rg1) against vascular remodeling and organ damage in spontaneously hypertensive rats (SHR). METHODS Male SHR were treated with 5, 10 or 20 mg/kg Rg1 through intraperiton...
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ژورنال
عنوان ژورنال: Life Sciences
سال: 2019
ISSN: 0024-3205
DOI: 10.1016/j.lfs.2019.116948